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The small amount of increased oxygen that is needed by the cells to improve their function does not necessarily require new blood vessel formation to be accomplished because with HBOT free oxygen molecules are dissolved directly into the cerebrospinal fluid Therefore these cells are no longer dependent on increased oxygen delivery from increased blood vessel formation that secondarily delivers a greater oxygen load because it carries more hemoglobin.

At times it may actually be the sudden removal of higher than normal oxygen concentrations that the body has adapted to rather than the higher levels of oxygen itself that may stimulate angioneogenesis There are reports that the new vessel formation in the retinas of premature infants who were on high doses of oxygen was stimulated by the rapid removal of oxygen and not from the oxygen itself.

However, as history has shown repeatedly throughout the years, convention is only convention until challenged, proven wrong, and then changed. A few of the multiple mechanisms demonstrating how HBOT may work for children with autism was originally and thoroughly researched over many months time by Dr. These mechanisms are shown below along with a couple others that have been suggested They include: The growth of new blood vessels has been shown to occur from soft chambers as well as from hard, and is a process that may continue to increase subsequent to discontinuing therapy for a period of time after oxygen loading.

Then most parents will state what they are doing, e.g. Because dissolved oxygen is not confined to a hemoglobin molecule, it can go wherever "body water goes" and therefore reach 'deeper tissues' more easily and more consistently than ever before Because no test is able to predict which child may and which child may not respond to extra pressure and/or extra oxygen (in contrast to excessive oxygen), I let nature take its course and prescribe a clinical trial of HBOT for all my children Though I let "nature take its course", I would not consider prescribing or administering HBOT to children with autism unless there was good scientific evidence to support its use.

"we're using 1.5, 1.75, or 2.0 atmospheres in a hard chamber with 100% oxygen, or we're using a soft chamber (also referred to as a mild chamber) at 1.3 atmospheres 'with or without a mask' to which 'concentrated oxygen' is be supplied at concentrations varying from 24% to 70%." Conventional wisdom states that unless one receives HBOT in a hard chamber with 100% oxygen at atmospheric pressures greater than 1.5 ATA, little or no benefit will be seen. Fortunately such evidence does exist, the body of which continues to accumulate, and the mechanisms of action by which HBOT may work for children with autism, as described below, may already be outdated by the time you read this.

Children with autism have difficulty handling viral infections, most likely due to immune dysfunction.

It has been postulated many times that children with autism have a chronic low grade viral gastroenteritis and viral encephalitits. I speculate that one of the primary reasons HBOT works so well for so many children whose abnormal stools improve once they start HBOT is because the chronic, low-grade, smoldering live viral load harbored in the intestinal mucosa (Wakefield/Krigsman hypothesis) does poorly when surrounded by higher oxygen concentrations.

Many children with autism have increased amounts of abnormal bacteria and yeast in their gastrointestinal tracts These same children have shown clinical improvements when this overgrowth phenomenon is treated with antibiotics, either by natural agents or pharmaceuticals.

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